CONG Mengyang,ZHAO Huihui,XU Xingming,DAI Shun,CHEN Chuanzhi,QIU Jianfeng,QIAN Xiuqing,QIN Shengxue.Hemodynamic Analysis on Anomalous Origin of the Right Coronary Artery from the Left Coronary Artery Sinus[J].Journal of medical biomechanics,2020,35(3):284-288
右冠状动脉起源于左冠状窦的血流动力学分析
Hemodynamic Analysis on Anomalous Origin of the Right Coronary Artery from the Left Coronary Artery Sinus
Received:May 15, 2019  Revised:June 27, 2019
DOI:
Chinese key words:  右冠状动脉  左冠状窦  血流动力学  血流速度  压力  壁面剪切力
English Key words:right coronary artery (RCA)  left coronary artery sinus  hemodynamics  flow velocity  pressure  wall shear stress (WSS)
Fund project:山东省泰山学者项目(ts201712065)
Author NameAffiliation
CONG Mengyang College of Mechanical and Electronic Engineering, Shandong University of Science and Technology 
ZHAO Huihui College of Radiology, Shandong First Medical University & Shandong Academy of Medical SciencesCenter for Medical Engineer Technology Research, Shandong First Medical University & Shandong Academy of Medical Sciences 
XU Xingming College of Mechanical and Electronic Engineering, Shandong University of Science and Technology 
DAI Shun Department of Radiology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine 
CHEN Chuanzhi Department of Radiology, Shanghai East Hospital 
QIU Jianfeng College of Radiology, Shandong First Medical University & Shandong Academy of Medical SciencesCenter for Medical Engineer Technology Research, Shandong First Medical University & Shandong Academy of Medical Sciences 
QIAN Xiuqing Department of Biomedical Engineering, Capital Medical University 
QIN Shengxue College of Mechanical and Electronic Engineering, Shandong University of Science and Technology 
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Chinese abstract:
      目的 通过计算流体动力学(computational fluid dynamics, CFD)分析右冠状动脉起源于左冠状窦(anomalous origin of the right coronary artery from the left coronary artery sinus, AORL)的血流动力学参数,从而有效评估疾病。方法 选取正常右冠状动脉(right coronary artery, RCA)和AORL两例个体病例,在Mimics软件中重建两个病例的血管模型,并将模型导入ANSYS CFX软件中进行血流动力学模拟计算,比较正常和AORL两种模型的血流动力学情况。结果 AORL模型右冠状动脉入口截面具有较小的血流量(9.35 cm3/s),有可能会导致右冠状动脉下游供血不足;AORL模型右冠状动脉急性拐角处的压力(13.78 kPa)相比于正常模型右冠状动脉(14.9 kPa)较低;AORL模型壁面剪切力(12.83 Pa)大于正常模型(9.74 Pa);AORL模型血管壁变形量较大。结论 AORL入口流速及拐角处压力均比正常RCA小,从而可能导致缺血症状发生。研究结果对临床上有效评估缺血等疾病具有理论指导意义。
English abstract:
      Objective To analyze the hemodynamic parameters of anomalous origin of the right coronary artery from the left coronary artery sinus (AORL) based on computational fluid dynamics (CFD), so as to make an evaluation of the disease. Methods A normal right coronary artery (RCA) case and an AORL case were selected. Two models were reconstructed in Mimics software and imported into ANSYS CFX software for hemodynamics simulation. The hemodynamics of normal RCA model and AORL model were compared. Results AORL model had a smaller volume flow (9.35 cm3/s), which might lead to insufficient blood supply downstream of the RCA; the pressure at the acute corner of AORL model (13.78 kPa) was lower than normal RCA model (14.9 kPa); the wall shear stress (WSS) of AORL model (12.83 Pa) was larger than that of normal RCA model (9.74 Pa); the total deformation of AORL model was relatively large. Conclusions The entrance velocity and pressure of AORL were lower than those of normal RCA, which might lead to ischemic symptoms. The research findings are of theoretical significance for the effective evaluation of ischemia and other diseases in clinic.
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